Enjoy Some
Southern Hospitality 


Nothing goes better with Southern BBQ than a cold pint of beer and a glass of whiskey.

Come in and appreciate some North Carolina Style BBQ, house-brewed beer, well-crafted cocktails, and more than 100 whiskeys.

2016 Best BBQ - SF Weekly

2016 Best Cocktail - SF Weekly

2016 Best Whiskey Bars in San Francisco — Thrillist

2014 Best Barbeque Restaurants in America — Opentable 





(415) 934-9300


2170 Mission St.
San Francisco, CA 94110


Mon 5–10:30p
Tues Closed
Wed 5–10:30p
Thur 5–10:30p
Fri 5–11:30p
Sat 3–11:30p
Sun 3–10:30p

Happy Thanksgiving you and your family! We will be closed on Thursday, November 23rd for the holiday. 

Week Long Fun

Who says all the fun happens on the weekend.

Let us help you get through the less eventful days with some delightful ways to stay entertained.


 Sundays & Mondays


Nothing goes better with BBQ than beer and whiskey. Come join us for $1 baby back ribs and buckets of Miller High Life ($15 for 6) on Sunday and Monday nights. We'll be serving them up until we run out!


Well, Well Wednesdays

$4 Well Drinks - All Night Long

It's Hump Day and what better way to usher in the race to the weekend than with $4 Well Drinks all night long. We'll make it through Hump Day together, one drink at a time.




We've got some pretty delicious house beers and as a thank you to all of our loyal patrons, we offer them for $4 all night long on Thursdays. It's our Locals Happy Hour.

Non-Profit Mondays

Join us every Monday and give back to the community through our Non-Profit Monday program. We donate 10% of all dine-in sales to a different non-profit partner each month.

October 2017: Napa and Sonoma County Fire Relief

All of the funds raised will be spread out evenly to fund the following organizations and their relative efforts:

Sonoma Valley Fire and Rescue Authority (Sonoma Valley Fire and Rescue Authority) 

Napa County Fire Department ( 

Lake County Fire and Rescue ( 

And relief fund(s) being set up for the people impacted by the fire.



Happy Hour

Join us for HAPPY HOUR Monday, Wednesday, Thursday & Friday from 5-7pm


Bar Bites

Smoked Chicken Wings $7

BBQ Tacos $7


Drink Specials

The Corn: 1/2 Cider + Shot of Old Overholt Rye $9

The Mel: Grapefruit Gimlet $7

The Katya: Kentucky Mule $5

The Hermilo: Blood & Sand $9

The Zack: Prohibition Sweet Tea $5

The Wells: Dickel No.12 + Pickle Back $8



Grab a Seat at the Bar


Southpaw has a 7 Barrel brewing system, which allows us to create unique batches of beer with each brew. We rarely brew the same beer twice and enjoy collaborating with our fellow brewers in the Bay area on creative recipes. We also offer unique rotating house sour beers and barrel-aged beer.


We strive to maintain a friendly and approachable atmosphere, while providing exceptional, balanced cocktails. We produce a great deal of our ingredients in-house and use high-quality local spirits whenever possible.   


With over 100 whiskeys at the bar and growing, Southpaw offers a strong working-class whiskey program. We offer 3 rotating whiskey flights that highlight and allow customers to compare different styles, distilleries and geographic areas.

*Named one of the Best Whiskey Bars in SF by Thrillist.

Whiskey Book

Southpaw rewards customers who try through 40 of our whiskies with a bottle of the one they enjoyed the most. Come in and order either a flight or glass of whiskey to get started.


Prohibition Sweet Tea
iced tea, cane sugar, vodka, lemon

18th and Ango
Rye whiskey, St. Germaine, Angostura bitters, Peychaud’s bitters, topped w/ sparkling wine

The WiFi Password
Rye whiskey, cynar, cardamom tincture, 

A Rub Down 
Tequila, grapefruit, lime, agave syrup, habanero tincture, Southpaw’s dry rub rim

Leggy Models
rye, cilantro/coriander syrup, lime

Mishi’s Regret No. 2
mezcal, cassis, lemon, habanero tincture

bourbon, lemon, smoked ginger, bitters, ginger ale

Huchin Punch
bourbon, fresh orange juice, agave, cardamom tincture

Spiced Russian 
Sailor Jerry Rum, coffee liqueur, milk, simple syrup

Earl Grey’s Anatomy
House-made Earl Grey infused vodka, lemon, honey syrup, egg whites

Jacob Is The Worst
George Dickle Rye, Amaro Angostura, Lemon, cinnamon syrup

House Old Fashioned
Bulliet Bourbon, bitters cubes, cane sugar, orange twist


Southpaw SF Lager

Southpaw Pale Ale

Southpaw Brett IPA

Southpaw Funky Blonde

Standard Deviant Kolsch

North Coast Stellar IPA

Social Kitchen Pilsner 

Laughing Monk Gose 

Henhouse Oyster Stout

21st Amendment El Sully Mexican Lager 

Tag and Jug SF Cider 

Standard Deviant Pale Ale 



Miller High Life

Anchor Liberty Ale 

Peregine Pilsner

Drake’s Brewing 1500 Pale Ale

Dogfish Head 90 min IPA

Boulevard Tell Tale Tart Sour

Hard Frescos Juicy Jamaica w/ Hibiscus

Leinenkugel Summer Shandy

Hard Frescos Cola Buena w/ Kola Nut

Sierra Nevada HopHunter IPA 


100 Proof Flight
Henry McKenna, James E Pepper Rye, Knob Creek Single Barrel 9yr

Hooker’s House Distillery Flight
Pinot Noir Barrel Aged Bourbon, Zinfandel Barrel Aged Rye, 7yr Sour Mash

Corbin Cash Whiskey Flight
Rye, Green House Blend, Sweet Potato Liqueur



Chateau de Campuget Rose 2015 

Dry Creek Chenin Blanc 2013 

Sisters Forever Chardonnay 2013 

Maggio Old Vine Zinfandel 2012 

Rib Shack Red Vintage Blend 2012 

Chandon Brut Classic NV


Southpaw is a casual brewpub that accepts limited reservations for our dining room. We reserve a portion of our dining room as well as our 20-seat bar for walk-ins. Walk-ins are seated on a first come first served basis and parties must be complete to be seated.

For larger parties of 8 or more, we do a family-style menu. We hold a credit card on file and only charge the card if the party does not show for the reservation. 

Reservations can me made online through our website, through Yelp reservations, or by calling the restaurant at 415-934-9300.

We’re looking forward to having you join us!